担任Pharmaceutical Science Advances杂志第一届青年编委

  以第一或通讯作者在Nat Chem Biol、PNAS (´2)、J Med Chem等高水平国际期刊发表论文14篇。研究成果被诺贝尔化学奖得主Kobilka教授等重点引用和评价。受邀在Chemical Reviews撰写相关进展总结和展望（Chem Rev, 2019, 119, 10520），被评为该刊年度TOP10阅读量文章，并入选ESI高被引论文，在国际上产生了重要影响。先后主持了国家自然科学基金面上项目、国家自然科学基金青年项目、四川大学双百人才工程、国家博士后创新人才支撑计划，以研究骨干身份参加国家自然基金创新研究群体项目、国家重点研发计划、国家“重大新药创制”等项目。受邀在“2023年国际分子模拟与人工智能应用学术会议”、“2023年中国药物化学学术会议暨中欧药物化学研讨会”做邀请报告。讲授本科生《蛋白质结构和药物设计》、研究生《药物设计与先导化合物优化》课程。所在的杨胜勇教授团队，一直聚焦药物分子设计新方法以及针对重大疾病的原创小分子靶向药物研究。研发的4个1类新药正在开展I-III期临床试验，多个候选药物进入临床前研究。热烈欢迎对药物分子设计、分子模拟、人工智能、化学生物学、药物化学感兴趣的研究生加入我们团队。

【代表性论著】

1. Xin Yang, Xuehui Wang, Zheng Xu, Chao Wu, Yangli Zhou, Yifei Wang, Guifeng Lin, Kan Li, Ming Wu, Anjie Xia, Jingming Liu, Lin Cheng, Jun Zou, Wei Yan, Zhenhua Shao*, Shengyong Yang*; Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1, Nature Chemical Biology, 2022, 18(8): 831-840.

2. Xin Yang, Pei Zhoua, Siyuan Shena, Qian Hua, Chenyu Tiana, Anjie Xia, Yifei Wang, Zhiqian Yang, Jinshan Nan, Yangli Zhou, Shasha Chen, Xiaowen Tian, Chao Wu, Guifeng Lin, Liting Zhang, Kexin Wang, Tao Zheng, Jun Zou, Wei Yan, Zhenhua Shao*, Shengyong Yang*; Entropy drives the ligand recognition in G protein-coupled receptor subtypes, PNAS, 2024, in press.

3. Siyuan Shen#, Chao Wu#, Guifeng Lin#, Xin Yang#, Yangli Zhou#, Chang Zhao, Zhuang Miao, Xiaowen Tian, Kexin Wang, Zhiqian Yang, Zhiyu Liu, Nihong Guo, Yueshan Li, Anjie Xia, Pei Zhou, Jingming Liu, Wei Yan, Bowen Ke*, Shengyong Yang*, and Zhenhua Shao*; Structure-based identification of a G protein–biased allosteric modulator of cannabinoid receptor CB1, PNAS, 2024, 121(24):e2321532121.

4. Jinshan Nan, Jingming Liu, Guifeng Lin, Shanshan Zhang, Anjie Xia, Pei Zhou, Yangli Zhou, Jiahao Zhang, Jinlong Zhao, Shiyu Zhang, Chong Huang, Yifei Wang, Qian Hu, Junxian Chen, Mingli Xiang, Xin Yang*, Shengyong Yang*; Discovery of 4-(1,2,4-Oxadiazol-5-yl)azepan-2-one Derivatives as a New Class of Cannabinoid Type 2 Receptor Agonists for the Treatment of Inflammatory Pain, Journal of Medicinal Chemistry, 2023, 66(5): 3460-3483.

5. Xin Yang, Guifeng Lin, Anjie Xia, Jingming Liu, Shiyu Zhang, Pei Zhou, Yiwei Wang, Jiahao Zhang, Yangli Zhou, Pei Chen, Yifei Wang, Tao Zheng, Linli Li, Shengyong Yang*; Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R), Journal of Chemical Information and Modeling, 2022, 62(20): 5009-5022.

6. Xin Yang, Jun Zou, Yifei Wang, Ying Xue, Shengyong Yang*; Role of water in the reaction mechanism and endo/exo selectivity of 1,3‐dipolar cycloadditions elucidated via quantum chemistry and machine learning, Chemistry – A European Journal, 2019, 25(35): 8289-8303.

7. Xin Yang, Yifei Wang, Ryan Byrne, Gisbert Schneider*, Shengyong Yang*; Concepts of Artificial Intelligence for Computer-Assisted Drug Discovery, Chemical Reviews, 2019, 119(18): 10520-10594.