代谢与转移实验室主任

反向蛋白质芯片中心副主任

1. Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer. Signal Transduct Target Ther. 2024. Zhang J, Zhao K, Zhou W, Kang R, Wei S, Shu Y, Yu C, Ku Y, Mao Y, Luo H, Yang J, Mei J, Pu Q, Deng S, Zha Z, Yuan G, Shen S, Chen Y*, Liu L*. 

2. Advances in oncolytic herpes simplex virus and adenovirus therapy for recurrent glioma. Front Immunol. 2023; 14:1285113. Hu M, Liao X, Tao Y, Chen Y*

3. Heat Shock Proteins in Non-Small-Cell Lung Cancer-Functional Mechanism.  Front Biosci (Landmark Ed). 2023;28(3). Zhou G, Pu Y, Zhao K, Chen Y*, Zhang G*.

4. Single-cell RNA sequencing highlights intratumor heterogeneity and intercellular network featured in adamantinomatous craniopharyngioma. Science Advances. 2023; 9(15). Yu Jiang, Jinlong Yang, Ruichao Liang, Xin Zan, Rangrang Fan, Baoyin Shan, Hao Liu, Li Li, Yue Wang, Min Wu, Xin Qi, Hongxu Chen, Qingqing Ren, Zhiyong Liu, Yuelong Wang, Jing Zhang, Peizhi Zhou, Qiang Li, Meng Tian, Jinhao Yang, Chaoyang Wang, Xueying Li, Shu Jiang, Liangxue Zhou, Gao Zhang*, Yaohui Chen*, Jianguo Xu*.

5. Targeting STT3A produces an anti-tumor effect in lung adenocarcinoma by blocking the MAPK and PI3K/AKT signaling pathway. Transl Lung Cancer Res. 2022, 11(6):1089-1107. Jiahan Cheng, Liang Xia, Xiaohu Hao, Fanyi Gan, Yuquan Bai, Chuanfen Zhang, Yonghong Mao, Yunke Zhu, Qiang Pu, Dong Won Park, Simona Tavolari, Jiandong Mei, Yaohui Chen*, Senyi Deng*, Lunxu Liu*.

6. Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors. Cancer Research Communications. 2022, 2 (6): 402–416. Joshy George#; Yaohui Chen#; Nourhan Abdelfattah; Keiko Yamamoto; Thomas D. Gallup; Scott I. Adamson; Brad Rybinski; Anuj Srivastava; Parveen Kumar; Min Gyu Lee; David S. Baskin; Wen Jiang; Jong Min Choi; William Flavahan; Jeffrey H. Chuang; Betty Y.S. Kim; Jiaqiong Xu; Sung Yun Jung; Kyuson Yun.

7. Perioperative ctDNA-based Molecular Residual Disease Detection for Non-Small Cell Lung Cancer: A Prospective Multicenter Cohort Study (LUNGCA-1). Clin Cancer Res.2021, 10.1158. Liang Xia#, Jiandong Mei#, Ran Kang#, Senyi Deng#, Yaohui Chen#, Ying Yang, Gang Feng, Yulan Deng, Fanyi Gan, Yidan Lin, Qiang Pu, Lin Ma, Feng Lin, Yong Yuan, Yang Hu, Chenglin Guo, Hu Liao, Chengwu Liu, Yunke Zhu, Wenping Wang, Zheng Liu, Yuyang Xu, Kaidi Li, Chuan Li, Qingyun Li, Ji He, Weizhi Chen, Xiaolong Zhang, Yingli Kou, Yun Wang, Zhu Wu, Guowei Che, Longqi Chen, Lunxu Liu.

8. Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target GeneExpression and Tumorigenesis. Cancer Research. 2019,80(5):1049-1063. Yaohui Chen, Runping Fang, Chen Yue, Guoqiang Chang, Peng Li, Qing Guo, Aidong Zhou, Sicong Zhang, Greg N Fuller, Xiaobing Shi, and Suyun Huang.

9. DNA-PK Facilitates piggyBac Transposition by Promoting Paired-End Complex Formation. PNAS. 2017, 114(28):7408-7413. Yan Jin#, Yaohui Chen#, Shimin Zhao, Kun-Liang Guan, Yuan Zhuang, Wen-Hao Zhou, Xiaohui Wu, Tian Xu. 

10. Wnt-Induced Deubiquitination of FoxM1 Ensures Nucleus β-catenin Transactivation. The EMBO Journal. 2016, 35(6):668-684. Yaohui Chen#, Yu Li#, Jianfei Xue#, Aihua Gong, Guanzhen Yu, Aidong Zhou, Kangyu Lin, Sicong Zhang, Nu Zhang, Cara J. Gottardi, Suyun Huang. 

11.  Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nature Communications.  2015, 6:6156. Jianfei Xue#,  Yaohui Chen#,  Yamei Wu,  Zhongyong Wang, Aidong Zhou, Sicong Zhang, Kangyu Lin, Kenneth Aldape, Sadhan Majumder, Zhimin Lu & Suyun Huang.